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The popular herbal extract St. John’s wort is more effective at treating the symptoms of depression than any antidepressant drug, and has fewer side effects, researchers from the Centre for Complementary Medicine in Munich have concluded.

“Overall, the St John’s Wort extracts tested in the trials were superior to placebo, similarly effective as standard anti-depressants, and had fewer side effects than standard anti-depressants,” lead researcher Klaus Linde said.

In a study published by the Cochrane Library, the researchers compiled the results of 29 prior trials, involving a total of 5,489 participants who were randomly assigned either St. John’s wort, a placebo, tricylclic antidepressants or selective serotonin reuptake inhibitors (SSRIs) to treat mild to moderately severe depression. All studies were double-blind, meaning that neither patients nor researchers knew what kind of treatment each participant was receiving.

St. John’s wort was found to be more effective than a placebo and at least as effective as both tricylics and SSRIs, but with fewer side effects. Patients receiving the herbal treatment were significantly less likely to drop out of studies due to negative side effects than those assigned to take tricyclic antidepressants.

The researchers called their study the most thorough to date, and possibly the first to show that St. John’s wort is effective at treating not only mild, but also severe depression (also known as major depression). St. John’s wort, known officially as Hypericum perforatum, is a native European perennial herb with distinctive yellow flowers and now grows wild in many parts of the Americas as well. It derives its common name from the tradition of harvesting its flowers on St. John’s day (June 24). Also known as Klamath weed or Tipton’s weed, the plant has been used for centuries as an herbal remedy for depression and sleeping problems.

In recent years, the popularity of the herbal antidepressant has soared as new concerns continue to emerge over pharmaceutical antidepressants, especially SSRIs. In Germany, doctors regularly prescribe it to children and teenagers. In the United Kingdom, it is currently used by two million people.

SSRIs have been shown to significantly increase the risk of suicide in those under the age of 18, and evidence suggests that they may have a similar effect on adults, as well. Recent evidence has also linked use of the drugs by pregnant women with an elevated risk of oral and heart-related birth defects.

With Western health care systems emphasizing drugs for the treatment of mental illness, however, many doctors feel they have no alternatives but to prescribe tricyclics or SSRIs, in spite of the risk. The new study may lead more doctors to prescribe St. John’s wort instead.

Another recent study, conducted by St. James’ University Hospital in Leeds, England, found that St. John’s wort was the only herbal supplement effective at treating depression, in contrast to cat’s claw, ginseng, gingko biloba, liquid tonic and royal jelly.

Researchers remain unsure precisely how St. John’s wort works, in part because the plant contains chemicals from at least seven different families. The most favored explanation is that the herb acts much like an SSRI, slowing the rate at which the neurotransmitter serotonin is removed from the brain. The chemical hyperforin is posited by some as the most active chemical agent in the herb, and has been linked to slowed uptake of not only serotonin but also the neurotransmitters dopamine, noradrenaline, GABA and glutamate. St. John’s wort extracts from which hyperforin has been removed, however, have still been shown to function as effective antidepressants.

Source: www.naturalnews.com

by Erin Bates

Drug advertisements and conventional doctors tell the public that depression is caused by an imbalance of a neurotransmitter in the brain called serotonin. This idea makes it seem that drugs that flood the brain with serotonin are the answer to depression, but there is no scientific evidence that drug therapy really works. In studies in which scientists lowered serotonin levels to induce depression, the experiment failed. Other studies found that dramatically increasing serotonin levels in the brain failed to relieve depression. So why do doctors persist in prescribing medications with side effects ranging from mood swings to suicidal or homicidal behaviors when those drugs may not even work?

There are treatment options that can relieve depression without swallowing pills. Many of the symptoms of depression can be directly linked to vitamin and mineral deficiencies in the standard American diet, which is largely comprised of empty carbs, caffeine and sugar. Depression, mood swings and fatigue often have a common cause: poor nutrition. Avoiding depression or recovering from a depressive episode is often as easy as changing your diet and boosting your consumption of key foods that deliver brain-boosting nutrients and help regulate brain chemistry.
The Five Foods for Beating Depression

Fish oils:
Contain omega-3 fatty acids. Research has shown that depressed people often lack a fatty acid known as EPA. Participants in a 2002 study featured in the Archives of General Psychiatry took just a gram of fish oil each day and noticed a 50-percent decrease in symptoms such as anxiety, sleep disorders, unexplained feelings of sadness, suicidal thoughts, and decreased sex drive. Omega-3 fatty acids can also lower cholesterol and improve cardiovascular health. Get omega-3s through walnuts, flaxseed and oily fish like salmon or tuna.
Brown Rice:
Contains vitamins B1 and B3, and folic acid. Brown rice is also a low-glycemic food, which means it releases glucose into the bloodstream gradually, preventing sugar lows and mood swings. Brown rice also provides many of the trace minerals we need to function properly, as well as being a high-fiber food that can keep the digestive system healthy and lower cholesterol. Instant varieties of rice do not offer these benefits. Any time you see “instant” on a food label, avoid it.
Brewer’s Yeast:
Contains vitamins B1, B2 and B3. Brewer’s yeast should be avoided if you do not tolerate yeast well, but if you do, mix a thimbleful into any smoothie for your daily dose. This superfood packs a wide assortment of vitamins and minerals in a small package, including 16 amino acids and 14 minerals. Amino acids are vital for the nervous system, which makes brewer’s yeast a no-brainer for treating depression.
Whole-grain oats:
Contain folic acid, pantothenic acid and vitamins B6 and B1. Oats help lower cholesterol, are soothing to the digestive tract and help avoid the blood sugar crash-and-burn that can lead to crabbiness and mood swings. Other whole grains such as kamut, spelt and quinoa are also excellent choices for delivering brain-boosting nutrients and avoiding the pitfalls of refined grains such as white flour.
Cabbage:
Contains vitamin C and folic acid. Cabbage protects against stress, infection and heart disease, as well as many types of cancers, according to the American Association for Cancer Research. There are numerous ways to get cabbage into your diet; toss it in a salad instead of lettuce, use cabbage in place of lettuce wraps, stir fry it in your favorite Asian dish, make some classic cabbage soup or juice it. To avoid gas after eating cabbage, add a few fennel, caraway or cumin seeds before cooking. Cabbage is also a good source of blood-sugar-stabilizing fiber, and the raw juice of cabbage is a known cure for stomach ulcers.
Also worth mentioning:
Foods like raw cacao, dark molasses and brazil nuts (high in selenium) are also excellent for boosting brain function and eliminating depression.
Things to avoid

If you feel you are depressed or at risk for depression, you also need to avoid certain foods and substances. Some commonly prescribed drugs — such as antibiotics, barbiturates, amphetamines, pain killers, ulcer drugs, anticonvulsants, beta-blockers, anti-Parkinson’s drugs, birth control pills, high blood pressure drugs, heart medications and psychotropic drugs — contribute to depression. If you are taking any of these, don’t quit them without talking to your doctor; but be aware that they may be contributing to your condition by depleting your body of depression-fighting vitamins and minerals.

You should also avoid caffeine, smoking and foods high in fat and sugar. Keeping your blood sugar stable and getting B vitamins is important for stabilizing your mood. Cacao can be good for mood because it releases endorphins in the brain, but watch out for milk chocolate and candy varieties high in sugar.

Other non-food things to do

Get plenty of sunshine. Natural sunlight is a proven cure for depression.
Engage in regular exercise at least three times per week. Exercise lifts and mood and alters brain chemistry in a positive way
Experience laughter. It’s good medicine.
Take a high quality range of mood boosting supplements to help even more…

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